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Anti-Human Follicle Stimulating Hormone Alpha (FSH-α )

Horseradish Peroxidase (HRPO)

Monoclonal Antibody

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Size

1.0 ml ( $178.00 )

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Prod. No.:	H116
Clone:	176
Isotype:	Mouse IgG
Conc.:	0.5 mg/ml
Pkg. Size:	1.0 ml

Description

Specificity:

Mouse Anti-Human Follicle Stimulating Hormone (FSH) (Clone 176) recognizes Human Follicle Stimulating Hormone. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:

Follicle-stimulating hormone (FSH) is a heterodimeric glycoprotein and is composed of alpha and beta subunits that regulates the development, growth, pubertal maturation, and reproductive processes of the human body. Alpha subunit is common to FSH and LH, while a unique beta subunit determines the biological specificity of each hormone.

Reporter Molecule:

Horseradish Peroxidase (HRPO) is an enzyme purified from horseradish root with a molecular weight of approximately 44 kDa.

Affinity:

4 X 10¹⁰

Host Species

Mouse

Immunogen

Purified Recombinant Human FSH (>98%)

Formulation

This horseradish peroxidase conjugate is supplied in a specially formulated stabilization diluent.(Leinco Prod. No.: S509)

Cross Reactivity

hCG Test Paired with Leinco Prod. No. C102, Clone No. 151: ihCG 100%, BhCG <1%, LH <4%, FSH <2%, TSH <1%. Paired with Leinco Prod. No. C103, Clone No. 152: ihCG 100%, BhCG <1%, LH <2%, FSH <1%, TSH <1%. Paired with Leinco Prod. No. C104, Clone No. 208: ihCg 100%, BhCG <1%, LH <1%, FSH <1%, TSH <1%. FSH Test Paired with Leinco Prod. No. F102, Clone No. 181: FSH 100%, BhCG <1%, LH <4%, ihCG **, TSH <1% ** 3,000 mIU/ml hCG causes 4.5% decrease in observed FSH. At higher concentrations of hCG, observed FSH reduced to zero. LH Test Paired with Leinco Prod. No. L100, Clone No. 196: LH 100%, BhCG <1%, FSH <1%, ihCG 57%, TSH <1%. Paired with Leinco Prod. No. L101, Clone No. 199: LH 100%, BhCG <1%, FSH <1%, ihCG 7%***, TSH <1%, *** 3,000 mIU/ml hCG causes 6.5% increases in observed LH.

Storage and Stability

Stable for at least one year when stored at 2°C - 8°C. Do not freeze.

Reported Applications

ELISA Det

Each investigator should determine their own optimal working dilution for specific applications.

Country of Origin

USA