Anti-Gαo Protein-Biotin [G106] : Leinco Technologies, excellence in early discovery research

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Anti-Bovine Gαo Protein

Biotin

Monoclonal Antibody

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Size

0.25 mg ( $334.00 )

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Prod. No.:	G106
Clone:	2A
Isotype:	Mouse IgG₁
Conc.:	0.1 mg/ml
Pkg. Size:	0.25 mg
Storage:	2-8°C Detailed storage instructions below.

Description

Specificity:

The anti Gαo protein antibody 2A recognizes Gαo protein from bovine, human, rat and mouse.

Antigen Distribution:

Antibody 2A reacts with bovine Gαo protein. Antibody showed 70% reactivity in human, 61% in rat and 54% in mouse of the bovine reactivity.

Background:

Heterotrimeric G proteins, composed of Gα and Gβγ subunits, transmit signals from cell surface receptors to cellular effector enzymes and ion channels. The Gαo protein is the most abundant Gα subtype in the nervous system, but it is also found in the heart. Its function is not completely known, although it is required for regulation of N-type Ca2+ channels in GH3 cells and also interacts with GAP43, a major protein in growth cones, suggesting a role in neuronal pathfinding.

Known Species Cross Reactivity: Ms+, Hu+, Rt+, Bov+

Host Species

Mouse

Formulation

This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.

Storage and Stability

This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.

Reported Applications

IHC (NBF/Par.), IP, WB

Each investigator should determine their own optimal working dilution for specific applications.

Country of Origin

USA

References

1. Li, X. et al. (1995) J. Neurochemistry 64:1107