Anti-Human Rhodopsin – Purified
Anti-Human Rhodopsin – Purified
Product No.: R127
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Clone RET-P1 Target Rhodopsin Formats AvailableView All Product Type Monoclonal Antibody Alternate Names RHO, MGC138309, MGC138311, OPN2, RP4, Visual Purple, Opsin 2 Isotype IgG1 Applications IHC FFPE , IP , WB |
Data
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.5 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient RRIDAB_2831700 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Anti-Human Rhodopsin (Clone RET-P1) recognizes a (Mr 39 kD) glycoprotein which is a visual pigment in mammals, birds, amphibians and reptiles.1,2,3 Antigen Distribution The Rhodopsin antigen is present on the photoreceptor cells in the retina. The antibody RET-P1 specifically labels the axons and synaptic pedicles of the rods being labelled.1,2,3 Background Rhodopsin, also known as visual purple, is expressed in metazoan photoreceptor cells. It is a pigment of the retina that is responsible for both the formation of the photoreceptor cells and the first events in the perception of light. Rhodopsins belong to the class of G-protein coupled receptors. Rhodopsin is extremely sensitive to light, and enables night-vision. Exposed to white light, the pigment immediately bleaches, and it takes about 30 minutes to regenerate fully in humans. Antigen DetailsResearch Area Cell Biology . Neuroscience References & Citations1. Barnstable, C. J. et al. (1980) Nature 286:231
2. Hicks, D. et al. (1987) J. Histochem. Cytochem. 35:1317
3. Treisman, J. E. et al. (1988) Molec. Cell. Biol. 8:1570
Technical ProtocolsIHC FFPE   |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
