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Anti-Mouse Vγ 2 T-Cell Receptor (TCR)
R-phycoerythrin (R-PE)
(Vγ 4)
Monoclonal Antibody
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Prod. No.:T213
Clone:UC3-10A6
Isotype:Armenian Hamster IgG
Pkg. Size:100 µg, 250 µg
Storage:2-8°C Detailed storage instructions below.
Description
Specificity:
This antibody reacts with Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes.

Antigen Distribution:
Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.

Background:
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

Reporter Molecule:
R-phycoerythrin (R-PE) has a molecular weight of 240 kDa and is purified from red algae. R-PE is an intensely bright phycobiliprotein with an absorption maxima at approximately 496, 546 and 565 nm, and a fluorescence emission maximum of ~578 nm.

Known Species Cross Reactivity: Ms+
Host Species
Armenian Hamster
Formulation
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.


Country of Origin
USA
References
Hedrick, S. M. et al. (1990) Nature. 343:714
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