Human Thyroid Stimulating Hormone
(HCG, GPH, GPHA1, CGA, Thyrotropin)
| Prod. No.: | T369 |
| Pkg. Size: | 1 mg, 10 µg, 50 µg |
| Storage: | -20°C Detailed storage instructions below. |
Description
Background:
Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3
Host Species
Human pituitary glands
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
References
1. (1998) Bowen A
2. McPherson et al. (2000) Placenta 24: 941
3. Wenger, R H et al. (2003) Wildmann's Clinical Interpretation of Laboratory Tests
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
