Product Datasheet
www.leinco.com
excellence in early discovery research       



Rabbit Anti-Human A Proliferating-Inducing Ligand (APRIL)
Purified No Carrier Protein
(CD256, TNFSF13, TALL2, TRDL1)
Polyclonal Antibody
Share |


Prod. No.:A154
Host:Rabbit
Conc.:0.5 mg/ml
Pkg. Size:0.1 mg, 0.5 mg, 1 mg
Storage:2-8°C Detailed storage instructions below.
Description
Specificity:
Rabbit Anti-Human APRIL recognizes an epitope in the extracellular domain of Human APRIL. This polyclonal antibody was purified using affinity chromatography.

Background:
A proliferation-inducing ligand (APRIL) is a TNF-like cytokine that stimulates tumor cell growth.1 It is of low abundance in normal tissues.2 APRIL acts as a proliferative factor in megakaryocytopoiesis, a developmental hematopoietic process responsible for progenitor cell differentiation to megakaryoblasts and megakaryocytes, leading to platelet formation.3 APRIL may be implicated in the regulation of tumor cell growth.2

Known Species Cross Reactivity: Hu+
Immunogen
APRIL (Extracellular Domain-1) Blocking Peptide (Leinco Prod. No.: A185)
Blocking Peptide
APRIL (Extracellular Domain-1) Blocking Peptide (Leinco Prod. No.: A185)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
WB
Each investigator should determine their own optimal working dilution for specific applications.


Country of Origin
USA
References
1. Sarah G. Hymowitz et al. (2004) J Mol Biol. 343: 283
2. (1998) Jürg Tschopp
3. Ruggero De Maria et al. (2004) Blood 104: 3169
Related Products
APRIL (Extracellular Domain-1) Blocking Peptide (Leinco Prod. No.: A185)
Anti-Human APRIL (Antigen Aff. Pur.) (Leinco Prod. No.: A206)
Anti-Human APRIL-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: A207)
APRIL (Extracellular Domain-2) Blocking Peptide (Leinco Prod. No.: A186)
Anti-Human APRIL (Extracellular Domain-2) (Leinco Prod. No.: A155)
Recombinant Mouse APRIL (A Proliferation-Inducing Ligand) (Leinco Prod. No.: A200)
Recombinant Human APRIL (Leinco Prod. No.: A413)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
359 Consort Drive | St. Louis, MO 63011 | (800) 538-1145 | (636) 527-5545 fax
800.538.1145 ® Copyright Leinco Technologies, Inc. 2006 – 2013