Product Datasheet
www.leinco.com
excellence in early discovery research       



Recombinant Human Glia Maturation Factor β (GMF-β)
(GMFB)
Share |


Prod. No.:G629
SourceE. Coli
Pkg. Size:10 µg, 1 mg
Storage:-20°C Detailed storage instructions below.
Description
Background:
Glial maturation factor-beta (GMF-beta) is isolated from brain tissues.1The expression of GMF-beta is largely limited to the brain2, especially glial cells and some neurons.3 GMF-beta is involved in the phenotypic differentiation of glial cells and neurons. It is expressed in the cytosol and on the cell surface of astrocytes.4,5 It is not secreted and presumably acts at short distances involving cell-to-cell interactions with target cells expressing a receptor. It is suggested that induction of GMF-beta expression in the kidney may play a key role in renal disease progression caused by proteinuria.

Source
E. Coli
State of Matter
Purity
>98% by SDS Page and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
Amino Acid Sequence
SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H


Country of Origin
USA
References
1. Lim R et al. (1989)Proceedings of the National Academy of Sciences (USA)86: 3901
Lim R et al. (1986)Cancer Research 46: 5241
3. Wang BR et al. (1992)Brain Research 591: 1
2. Zaheer A et al. (1993)Journal of Neurochemistry 60: 914
4. Lim R et al. (1990)Cell Regulation 1: 741
5. Lim R et al. (1990)Proceedings of the National Academy of Sciences (USA) 87: 5233
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
359 Consort Drive | St. Louis, MO 63011 | (800) 538-1145 | (636) 527-5545 fax
800.538.1145 ® Copyright Leinco Technologies, Inc. 2006 – 2012