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Recombinant Mouse Insulin-Like Growth Factor I (IGF-I)
Purified No Carrier Protein
(Somatamedin C, IGF-IA)
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Prod. No.:I-239
SourceE. coli
Pkg. Size:50 µg, 1 mg
Storage:-20°C to -70°C Detailed storage instructions below.
Description
Background:
The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions.

Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Mouse IGF-I is Mr 7.6 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
gpetlcgael vdalqfvcgp rgfyfnkptg ygssirrapq tgivdeccfr scdlrrlemy caplkptkaa



Country of Origin
USA
Related Products
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Anti-Human IGF-I-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: I-235)
Anti-Mouse IGF-I-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: I-240)
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Recombinant Human IGF-I R (Leinco Prod. No.: I-841)
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Recombinant Human IGF-I (Leinco Prod. No.: I-180)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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