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Recombinant Hexarelin (Hexa) (GRHL) | Prod. No.: | H1470 | | Pkg. Size: | 500 mg, 20 mg, 100 mg | | Storage: | -20°C Detailed storage instructions below. |
Description Background: Hexarelin is a synthetic growth hormone secretagogue (GHS), which possesses a variety of cardiovascular protective activities mediated via the GHS receptor (GHSR), including improving cardiac dysfunction and remodeling. Hexarelin inhibits DNA and collagen synthesis and proliferation of cardiac fibroblasts through activation of both GHSR and A(2)R and diminishment of ANG II-induced increase in TGF-beta expression and release.1 Hexarelin could be clinically useful to stimulate GH (Growth Hormone) secretion in humans.2 State of Matter Purity >98% by SDS Page and HPLC Storage and Stability The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Endotoxin <0.125 EU/µg Country of Origin USA References 1. Cao JM et al. (2007) Am J Physiol Heart Circ Physiol. 293: H2952
2. F Camanni et al. (1994) J Clin Endocrin & Metabolism 78: 693
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.