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Recombinant Mouse Tumor Necrosis Factor Receptor I (TNF RI)
Purified No Carrier Protein
(TNFRSF1A, P55, TBP1, CD120a, FPF, MGC19588, TNF-R, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55-R, p60)
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Prod. No.:T395
SourceNSO Cells
Pkg. Size:50 µg, 1 mg
Storage:-20°C to -70°C Detailed storage instructions below.
Description
Background:
Tumor necrosis factor receptor superfamily, member 1A, (TNFRI) also known as TNFRSF1A or CD120A is the principal receptor through which many of the pro-inflammatory activities of TNF-alpha are mediated.1 TNFRI contains a death domain through which it interacts with other death-domain proteins to promote cellular responses.2 It regulates immune and inflammatory responses.3

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Mouse TNF RI is Mr 48.6 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 70 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>90% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
l vpslgdrekr dslcpqgkyv hsknnsicct kchkgtylvs dcpspgrdtv crecekgtft asqnylrqcl scktcrkems qveispcqad kdtvcgcken qfqrylseth fqcvdcspcf ngtvtipcke tqntvcncha gfflresecv pcshckknee cmklclpppl anvtnpqdsg tadiegrmdp kscdkthtcp pcpapellgg psvflfppkp kdtlmisrtp evtcvvvdvs hedpevkfnw yvdgvevhna ktkpreeqyn styrvvsvlt vlhqdwlngk eykckvsnka lpapiektis kakgqprepq vytlppsrde ltknqvsltc lvkgfypsdi avewesngqp ennykttppv ldsdgsffly skltvdksrw qqgnvfscsv mhealhnhyt qkslslspgk



Country of Origin
USA
References
1. Reza Dana et al. (2000) Arch Ophthalmol. 118: 1666
2. Donner DB et al. (2008) J Immunol. 181: 1288
3. Pasparakis M et al. (2008) Nat Immunol. 9: 1015
Related Products
Anti-Mouse TNF RI (Leinco Prod. No.: T440)
Anti-Human TNF RI-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: T479)
Anti-Human TNF RI-Fluorescein (FITC) (Leinco Prod. No.: T506)
Anti-Human TNF RI-R-phycoerythrin (R-PE) (Leinco Prod. No.: T507)
Anti-Human TNF RI (Leinco Prod. No.: T428)
Anti-Mouse TNF RI (Leinco Prod. No.: T436)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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