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Recombinant Mouse Tumor Necrosis Factor Receptor II (sTNF RII)
Purified No Carrier Protein
(TNFRSF1B, p75, CD120b, TBPII, TNF-R75, TNFBR, TNFR2, TNFR80, p75TNFR)
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Prod. No.:T394
SourceE. coli
Pkg. Size:50 µg, 1 mg
Storage:-20°C to -70°C Detailed storage instructions below.
Description
Background:
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types1 and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells.2

Source
E. coli
Molecular Weight
The predicted molecular weight of Recombinant Mouse TNF RII is Mr 25 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Purity
>97% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
vpaqvvlt pykpepgyec qisqeyydrk aqmccakcpp gqyvkhfcnk tsdtvcadce asmytqvwnq frtclscsss cttdqveira ctkqqnrvca ceagrycalk thsgscrqcm rlskcgpgfg vassrapngn vlckacapgt fsdttsstdv crphricsil aipgnastda vcapesptls aiprtlyvsq peptrsqpld qepgpsqtps iltslgstpi ieqstkgg



Country of Origin
USA
References
1. Zuckerman KS et al. (1998) Cancer Res. 58: 2217
2. (2007) BD Biosciences
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Anti-Human sTNF RII (Antigen Aff. Pur.) (Leinco Prod. No.: T476)
Anti-Mouse sTNF RII-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: T490)
Recombinant Human TNF RII (aa 24-206) (TNFRSF1B) (Leinco Prod. No.: T522)
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PN:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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