Anti-Human CD16
Fluorescein (FITC)
(FcγRIII)
Monoclonal Antibody
| Prod. No.: | C466 |
| Clone: | GRM1 |
| Isotype: | Mouse IgG2a |
| Conc.: | 0.1 mg/ml |
| Pkg. Size: | 100 tests |
Description
Specificity:
Mouse Anti-Human CD16 (Clone GRM1) recognizes Human CD16. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. The CD16 molecule has been described as the low affinity Fc receptor (FcRIII) for complexed IgG which may exist either as a transmembranous form or as glycosyl-phosphatidylinositol form. It is expressed on NK cells, granulocytes (PMN) and macrophages. The GPI-linked form is also expressed on neutrophils.
Antigen Distribution:
Granulocytes: >98%
LGL cells: >85%
Peripheral blood lymphocytes: 12 + 8%
Thymocytes: <1%
Monocytes: <1%
B cells (CD20+): <1%
T cells (CD3+): <1%
Reporter Molecule:
Fluorescein (FITC) is a small fluorescent organic molecule with a molecular weight of 473 daltons with an absorbance maximum of ~492 nm and an emission maximum of ~518 nm.
Known Species Cross Reactivity: Hu+
Host Species
Mouse
Formulation
This conjugate is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Storage and Stability
Store at 2-8°C protected from light. DO NOT FREEZE. For long term storage aliquot conjugate into working volumes and store at 2-8°C for up to a year.
Country of Origin
USA
References
1. Leukocyte Typing V (1995) Oxford University Press
2. Leukocyte Typing IV (1989) Oxford University Press
3. Leukocyte Typing III (1987) Oxford University Press
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
