Anti-Human Chorionic Gonadotropin (HCG)
Horseradish Peroxidase (HRPO)
(CGB, CGB3, hCGB, MGC119822)
Monoclonal Antibody
| Prod. No.: | H102 |
| Clone: | 150 |
| Isotype: | Mouse IgG |
| Conc.: | 0.5 mg/ml |
| Pkg. Size: | 1.0 ml |
Description
Specificity:
Mouse Anti-Human Chorionic Gonadotropin (HCG) (Clone 150) recognizes Human Chorionic Gonadotropin. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced in pregnancy that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the corpus luteum of the ovary and thereby maintain progesterone production that is critical for a pregnancy in humans. hCG may have additional functions; for instance, it is thought that hCG affects the immune tolerance of the pregnancy. Early pregnancy testing, in general, is based on the detection or measurement of hCG. Because hCG is produced also by some kinds of tumor, hCG is an important tumor marker, but it is not known whether this production is a contributing cause or an effect of tumorigenesis.
Reporter Molecule:
Horseradish Peroxidase (HRPO) is an enzyme purified from horseradish root with a molecular weight of approximately 44 kDa.
Affinity:
1 X 1010
Host Species
Mouse
Immunogen
Purified Recombinant Human HCG (>98%)
Formulation
This horseradish peroxidase conjugate is supplied in a specially formulated stabilization diluent.(Leinco Prod. No.: S509)
Cross Reactivity
hCG Test
Paired with Leinco Prod. No. C103 Clone No. 152: ihCG 111%, BhCG 100%, LH < 3%, FSH < 1%,
TSH < 1%.
LH Test
Paired with Leinco Prod. No. L100 Clone No. 196: LH 100%, BhCG < 1%, FSH < 1%, ihCG 78%,
TSH < 1%.
Paired with Leinco Prod. No. L101 Clone No. 199: LH 100%, BhCG < 1%, FSH < 1%, ihCG 3%,
TSH < 1%.
Storage and Stability
Stable for at least one year when stored at 2°C - 8°C. Do not freeze.
Reported Applications
ELISA Det,
ELISA Sandwich Assay: 1234
Each investigator should determine their own optimal working dilution for specific applications.
Country of Origin
USA
References
1. (2007 Feb. 23) Int. J. Gynaecol. Obstet.
2. (2007 Feb. 15) Fertil. Steril.
3. (2007 Feb. 9) Fertil. Steril.
4. (2007 Feb. 9) Fertil. Steril.
5. (2006 Mar.) Taiwan J. Obstet. Gynecol. 45(1):48
6. (2007 Jan. 26) Fertil. Steril.
Related Products
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
