Anti-Human Cytokeratin 19 – Purified

Anti-Human Cytokeratin 19 – Purified

Product No.: C162

[product_table name="All Top" skus="C162"]

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Clone
BA17
Target
Cytokeratin 19
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
PTPN22, PTPN8 (former), PEP
Isotype
IgG1
Applications
ICC
,
IHC FFPE
,
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Mammary organoids
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Anti-Human Cytokeratin 19 (clone BA17) reacts with the smallest human cytokeratin (Mr 40 kDa).1 The antibody reacts specifically with cytokeratin 19 and has no reactivity with other cytokeratins.
Antigen Distribution
Anti-Cytokeratin 19 reacts strongly with luminal (secretory) epithelial cells but does not stain the basal (myoepithelial) cells. There is a subset of secretory epithelial cells which were Keratin 19- and are thought to be precursors to keratin 19+ cells.1,2
Background
Cytokeratin 19, a type I intermediate filament protein, it is the smallest known acidic cytokeratin. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours.

Antigen Details

Research Area
Cell Biology
.
Neuroscience
.
Neuroscience Cell Markers

References & Citations

1. Bartek J. et al. (1985) J. Cell Sci. 75:17 2. Bartek J. et al. (1985) Int. J. Cancer 36:299
ICC
IHC FFPE
General Western Blot Protocol

Formats Available

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Products are for research use only. Not for use in diagnostic or therapeutic procedures.