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Anti-Rat PCNA (PCNA) Biotin

Monoclonal Antibody

Prod. No.:P104
Isotype:Mouse IgG2a κ
Conc.:0.1 mg/ml
Pkg. Size:50 µg, 100 µg, 200 µg
Starting at:$70.00
Availability:In Stock
Storage:2-8°C Detailed storage instructions below.
Anti-PCNA (Proliferating Cell Nuclear Antigen) recognizes polymerase delta accessory protein (Mr 36 kDa).1,3 This auxiliary protein is also known as cyclin and experiments strongly suggest that PCNA is essential for cellular DNA synthesis.2,3

Antigen Distribution:
Anti-PCNA staining is almost entirely confined to the nucleus and may show a diffuse or granular pattern or a mixture of both. Dominant PCNA expression begins during late G1 phase and is present through S phase of the cell cycle.

Known Species Cross Reactivity: Ms+, Hu+, Rt+, All vertebrate and insect species tested
Host Species
Rat PCNA made in the protein A vector pR1T2T
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Reported Applications
Each investigator should determine their own optimal working dilution for specific applications.

Country of Origin
1. Tan, C. et al. (1987) Nucleic Acids Research 15:9299
2. Zuber, M. et al. (1989) Molec. Cell. Biol. 9:57
3. Waseem, H. N. et al. (1990) J. Cell Sci. 96:121
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