Anti-Human GFRα-1 (Intermediate Domain)

Anti-Human GFRα-1 (Intermediate Domain)

Product No.: G576

[product_table name="All Top" skus="G576"]

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Target
Glial Cell Line-Derived Neurotropic Factor soluble Receptor Alpha 1
Product Type
Polyclonal Antibody
Alternate Names
GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, MGC23045, RET1L, RETL1, TRNR1
Applications
IHC FFPE
,
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:G579
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human GDNF Family Receptor Alpha 1 (GFRα-1) recognizes Human GFRα-1. This polyclonal antibody was purified using affinity chromatography.
Background
GDNF family receptor alpha 1, also known as GFRA1 is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. GFRalpha1 functions as a ligand-induced cell adhesion molecule (LICAM) to establish precise synaptic contacts and induce presynaptic differentiation.1

Antigen Details

NCBI Gene Bank ID

References & Citations

1. Ibáñez CF. et al. (2007)Nat Neurosci. 10 : 293
IHC FFPE
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.