Recombinant Mouse Lungkine

CXCL15 is a small cytokine belonging to the CXC chemokine family that is highly abundant in epithelial cells of the lung¹ and can also be found in other mucosal organs such as the urogenital and gastrointestinal tracts, and in endocrine organs like the adrenal gland. CXCL15 recruits neutrophils during pulmonary inflammation² at which time it acts to specifically recruit neutrophils and direct them into the lung airway.

The biological activity of Mouse Lungkine is determined by its ability to chemoattract human neutrophils using a concentration range of 20.0-100.0 ng/ml.

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Met

Lyophilized

The predicted molecular weight of Recombinant Mouse CXCL15 is Mr 16.5 kDa.

16.5

This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH₃CN) and 0.1% trifluoroacetic acid (TFA) with BSA as a carrier protein.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

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1. Zlotnik, A. et al. (1999) J Immunol. 162: 5490
2. Lorenz, RG. et al. (2007) J Histochem Cytochem. 55: 515