Recombinant Human MIG (CXCL9)

Recombinant Human MIG (CXCL9)

Product No.: M160

[product_table name="All Top" skus="M160"]

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Alternate Names
CMK, Humig, SCYB9, Crg-10, CXCL9
Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Human

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Product Size
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Background

Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon (MIG). CXCL9 is a T-cell chemoattractant, which is induced by IFN-γ. Mig may be important not only to recruit T cells to peripheral inflammatory sites, but also in some cases to maximize interactions among activated T cells, B cells, and dendritic cells within lymphoid organs to provide optimal humoral responses to pathogens.1

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.01EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human MIG was determined by its ability to chemoattract mCXCR3 transfected mouse BaF/3 cells. The expected ED<sub>50</sub> for this effects is typically 0.1 - 0.4 μg/ml.
Protein Accession No.
Amino Acid Sequence
tpvvrkgr cscistnqgt ihlqslkdlk qfapspscek ieiiatlkng vqtclnpdsa dvkelikkwe kqvsqkkkqk ngkkhqkkkv lkvrksqrsr qkktt
N-terminal Sequence Analysis
Thr23
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human MIG is Mr 11.7 kDa.
Predicted Molecular Mass
11.7
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Farber, JM. et al. (2002) J. Immunol. 169: 1433
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
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Prod No.
Description
M160
Products are for research use only. Not for use in diagnostic or therapeutic procedures.