Recombinant Mouse TECK

Chemokine (C-C motif) ligand 25 (CCL25) is a small cytokine belonging to the CC chemokine family that is also known as TECK (Thymus-Expressed ChemoKine). CCL25 is believed to play a role in the development of T-cells.¹ It is chemotactic for thymocytes, macrophages, and dendritic cells. CCL25 is expressed in the small intestinal epithelium and plays an important role in mediating lymphocyte recruitment to this site.² CCL25 is also highly expressed in the thymus, where it binds to its receptor CCR9 on thymocytes promoting migration and activation.³

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Met

Lyophilized

The predicted molecular weight of Recombinant Mouse CCL25 is Mr 14 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 16-17 kDa.

14

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Vacari, AP. et al. (1997) Immunity 7: 291
2. Agace, W. et al. (2006) J Immunol. 176: 3642
3. Teixidó, J. et al. (2007) J Leukoc Biol. 82: 380