AffiPure™ Normal Rabbit IgG F(ab’)2 fragment

Pricing & Details

  
Product Type
AffiPure™ Purified Immunoglobulin
Prod No.
Size
Price
Avail.
Qty
Add to cart
R1373-2.0 mg
2.0 mg
$125.00
In stock
R1373-10 mg
10 mg
$398.00
In stock
  

Product Details

Host Species
Rabbit
Product Concentration
5.0 - 15 mg/ml
Formulation
This product has been aseptically packaged and formulated in phosphate buffered saline (PBS) pH 7.1-7.5 with no carrier proteins or preservatives.
Product may be provided with carrier proteins or preservatives by request
State of Matter
Sterile Liquid
Storage and Handling
Store at 2-8° C under sterile conditions
Expiration Date
One year after date of receipt
See directions on lot specific datasheets, as information may periodically change.

Description

Background
AffiPure™ Normal Rabbit IgG F(ab')2 fragment antibodies eliminate non-specific binding between Fc portions of antibodies and Fc receptors on cells such as macrophages, dendritic cells, neutrophils, NK cells or B cells. F(ab')2 fragment antibodies are generated by optimal pepsin digestion of the antisera followed by antigen affinity chromatography to eliminate the presence of Fc fragments and whole molecules, as well as leave intact some of the hinge region. F(ab')2 fragments have two antigen-binding F(ab) portions linked by disulfide bonds, and therefore are divalent with a molecular weight of about 110 kDa. F(ab')2 fragments penetrate tissues more efficiently than whole molecules due to their smaller size. This product contains a sufficient quantity of endogenous IgG to block nonspecific binding sites on fixed samples and assay substrates. While most commonly used in flow cytometry this product is useful in other applications such as ELISA, IHC, ICC, Blocking and as a control.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.