Anti-Human CD105 – FITC

Pricing & Details

Product No.C774
Clone
8E11
Protein
CD105
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Endoglin, Ancillary TGF-beta Receptor
Isotype
Mouse
IgM
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C774-100 tests
100 tests
$390.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
PMA-induced U-937 cells. U-937 is an human lymphoma cell line that expresses markers and properties of monocytes.
Formulation
This conjugate is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Storage and Handling
Store at 2-8°C protected from light. DO NOT FREEZE. For long term storage aliquot conjugate into working volumes and store at 2-8°C for up to a year.
Country of Origin
USA
Shipping
Next Day Ambient
Excitation Laser
Blue Laser (488 nm)
Applications and Recommended Usage?
Quality Tested by Leinco
FC The suggested concentration for this 8E11 antibody for staining cells in flow cytometry is ≤ 1 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Additional Reported Applications For Relevant Conjugates ?
IHC (Frozen)
IP
For specific conjugates of this clone, review literature for suggested application details.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human CD105 (Clone 8E11) recognizes Human CD105. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Endoglin is an endothelial homodimeric membrane antigen containing the tripeptide sequence RGD, which is a recognition motif for adhesion receptors of the integrin family. It has been proposed that endoglin is a TGF-beta receptor. Endoglin is a glycoprotein present on endothelial cells of capillaries, arterioles and venules in a variety of tissues and at low levels on acute lymphoblastic and myelocytic leukemia cells.

Antigen Details

Protein
Ligand/Receptor
TGF-ß1, TGF-ß3
PubMed
NCBI Gene Bank ID

References & Citations

1. Lastres, P. et. al. (1994) Biochem. J. 301:765 2. Westenend, P. J. et al. (1994) J. Am. Soc. Neph. 5:822 3. Fernandez-Ruiz, E. et al. (1993) Cell Genet. 64:204 4. Bellon, T. et al. (1993) Eur. J. Immunol. 23:2340 5. Lastres, P. et al. (1992) Eur. J. Immunol. 22:393 6. O'Connell, P. J. et al. (1992) Clin. Exp. Immunol. 90:154 7. Lopez-Casillas, F. et al. (1991) Cell 67:785
Flow Cytometry

Formats Available

Prod No.
Description
C774
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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