Anti-Human CD49f (Integrin α6) (Clone 4F10) – Purified

Home/Primary Monoclonal Antibodies/SurfaceTag Human CD Markers/Anti-Human CD49f (Integrin α6) (Clone 4F10) – Purified

Pricing & Details

Product No.C627
Clone
4F10
Protein
CD49f
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Integrin α6
Isotype
Mouse
IgG2b
Applications
FC
,
IP
Prod No.
Size
Price
Avail.
Qty
Add to cart
C627-0.1 mg
0.1 mg
$450.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
Cell Line SW/222 (Human Colorectal Carcinoma)
Product Concentration
0.1 mg/ml
Formulation
This purified monoclonal antibody is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Storage and Handling
For use within 1 month of purchase store at 2-8°C. For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human CD49f (Clone 4F10) recognizes Human CD49f. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody is specific to the integrin alpha6 chain which is expressed on epithelial and endothelial basement membrane. The VLA alpha6 chain, which consists of a single disulphide linked 120 kDa subunit and a small doublet subunit of 25/30 kDa, is non-covalently associated with the VLA beta-chain (CD29) in VLA-6 or alpha6/beta1 complex or with integrin beta4 chain (alpha6/beta4) The antigen is also expressed on platelets, monocytes, thymocytes and T-lymphocytes.

Antigen Details

Protein
Ligand/Receptor
With integrin β1 (CD29) forms VLA-6, with integrin β4 (CD104) forms a6β4 integrin; laminin and kalinin are ligands for these receptors
PubMed
NCBI Gene Bank ID

References & Citations

1. Ramaswamy, A. et al. (1995) J. Path. 176(3):227 2. Dobson, H. et al. (1994) GUT 35:1343 3. Pignatelli, M. et al. (1992) Human Pathol. 23:1159
Flow Cytometry
Immunoprecipitation Protocol

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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