Anti-Human CD55 (Clone 143-30) – PE

Home/Primary Monoclonal Antibodies/SurfaceTag Human CD Markers/Anti-Human CD55 (Clone 143-30) – PE

Pricing & Details

Product No.C649
Clone
143-30
Protein
CD55
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
DAF
Isotype
Mouse
IgG1
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C649-100 tests
100 tests
$429.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
PHA Activated Peripheral Blood Mononuclear Cells
Formulation
This conjugate is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Storage and Handling
Store at 2-8°C protected from light. DO NOT FREEZE. For long term storage aliquot conjugate into working volumes and store at 2-8°C for up to a year
Country of Origin
USA
Shipping
Next Day 2-8°C
Excitation Laser
Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human CD55 (Clone 143-30) recognizes Human CD55. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-Human CD55 is the complement regulatory protein decay accelerating factor (DAF). It is a 70 kDa glycoprotein (in erythrocytes) anchored in the membrane by a glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also one N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating of decay of both classical and alternative pathways. DAF has a wide distribution on cells in non-hematopoietic tissues, particularly epithelium and endothelium and is specifically found at the foetal-maternal interface in placenta. Soluble forms of DAF are found, for example, in plasma, saliva, urine, etc. FUSION PARTNER: NS1 myeloma cell line.

Antigen Details

Protein
Ligand/Receptor
C3b, C4b, CD97, Coxsackie viruses
PubMed
NCBI Gene Bank ID

References & Citations

1. Holanda, K. et al. (2002) Blood 100:341 2. Leukocyte Typing V (1995) Oxford Univ. Press 3. Lubin, D. M. et al. (1989) Ann. Rev. Immunol. 7:35 4. Daniels, G. L. (1989) Vox Sang. 56:205 5. Leukocyte Typing IV (1989) Oxford Univ. Press
Flow Cytometry

Formats Available

Prod No.
Description
C649
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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