Anti-Human CD61 (Integrin β3) (Clone PM6/13) – Purified
Anti-Human CD61 (Integrin β3) (Clone PM6/13) – Purified
Product No.: C616
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Clone PM6/13 Target CD61 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Integrin β3 Isotype IgG1 Applications FC , IHC FFPE , IP , WB |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Human Platelet Plasma Membrane Product Concentration 0.1 mg/ml Formulation This purified monoclonal antibody is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative. Storage and Handling For use within 1 month of purchase store at 2-8°C. For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2829781 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Anti-Human CD61 (Clone PM6/13) recognizes Human CD61. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. The antibody is specific for the 110 kDa platelet glycoprotein GP IIIa and inhibits platelet aggregation and activation induced by thrombin and collagen. The platelet glycoprotein is the integrin beta3 chain of the vitronectin receptor and GPIIb/IIIa. The antigen is present on platelets and megakaryocytes. Antigen Distribution Platelets: >98% Megakaryocytes: >98% Granulocytes: 0% Monocytes: 0% LGL cells: 0% B cells: 0% T cells: 0% Peripheral blood lymphocytes: 0% Antigen DetailsLigand/Receptor Fibronectin, vitronectin, vWF PubMed NCBI Gene Bank ID UniProt.org References & Citations1. Tsopanoglou, N. E. et al. (2002) Am. J. Physiol. Cell Physiol. 283:C1501
2. Boettiger, D et al. (2001) Mole. Biol. of the Cell 12(5): 1227
Technical Protocols IHC FFPE   |
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Formats Available
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
