Anti-Human CD61 (Integrin β3) (Clone PM6/13) – Purified

Anti-Human CD61 (Integrin β3) (Clone PM6/13) – Purified

Product No.: C616

[product_table name="All Top" skus="C616"]

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Clone
PM6/13
Target
CD61
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Integrin β3
Isotype
IgG1
Applications
FC
,
IHC FFPE
,
IP
,
WB

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Select Product Size
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Human Platelet Plasma Membrane
Product Concentration
0.1 mg/ml
Formulation
This purified monoclonal antibody is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Storage and Handling
For use within 1 month of purchase store at 2-8°C. For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Specificity
Mouse Anti-Human CD61 (Clone PM6/13) recognizes Human CD61. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. The antibody is specific for the 110 kDa platelet glycoprotein GP IIIa and inhibits platelet aggregation and activation induced by thrombin and collagen. The platelet glycoprotein is the integrin beta3 chain of the vitronectin receptor and GPIIb/IIIa. The antigen is present on platelets and megakaryocytes.
Antigen Distribution

Platelets: >98%
Megakaryocytes: >98%
Granulocytes: 0%
Monocytes: 0%
LGL cells: 0%
B cells: 0%
T cells: 0%
Peripheral blood lymphocytes: 0%

Antigen Details

Ligand/Receptor
Fibronectin, vitronectin, vWF
PubMed
NCBI Gene Bank ID

References & Citations

1. Tsopanoglou, N. E. et al. (2002) Am. J. Physiol. Cell Physiol. 283:C1501 2. Boettiger, D et al. (2001) Mole. Biol. of the Cell 12(5): 1227
Flow Cytometry
IHC FFPE
Immunoprecipitation Protocol
General Western Blot Protocol

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.