Anti-Human CD61 (Integrin β3) (Clone PM6/13) – PE

Anti-Human CD61 (Integrin β3) (Clone PM6/13) – PE

Product No.: C618

[product_table name="All Top" skus="C618"]

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Clone
PM6/13
Target
CD61
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Integrin β3
Isotype
IgG1
Applications
FC

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Human Platelet Plasma Membrane
Formulation
This conjugate is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative.
Storage and Handling
Store at 2-8°C protected from light. DO NOT FREEZE. For long term storage aliquot conjugate into working volumes and store at 2-8°C for up to a year.
Country of Origin
USA
Shipping
Next Day 2-8°C
Excitation Laser
Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human CD61 (Clone PM6/13) recognizes Human CD61. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. The antibody is specific for the 110 kDa platelet glycoprotein GP IIIa and inhibits platelet aggregation and activation induced by thrombin and collagen. The platelet glycoprotein is the integrin beta3 chain of the vitronectin receptor and GPIIb/IIIa. The antigen is present on platelets and megakaryocytes.
Background
Anti-CD61 may be used to identify platelets and megakaryocytes. It may also be used in studies to characterize leukemias and in research of cell adhesion molecules.
Antigen Distribution

Platelets: >98%
Megakaryocytes: >98%
Granulocytes: 0%
Monocytes: 0%
LGL cells: 0%
B cells: 0%
T cells: 0%
Peripheral blood lymphocytes: 0%

Antigen Details

Ligand/Receptor
Fibronectin, vitronectin, vWF
PubMed
NCBI Gene Bank ID

References & Citations

1. Tsopanoglou, N. E. et al. (2002) Am. J. Physiol. Cell Physiol. 283:C1501 2. Boettiger, D et al. (2001) Mole. Biol. of the Cell 12(5): 1227
Flow Cytometry

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.