Anti-Human sCD22

Anti-Human sCD22

Product No.: C220

[product_table name="All Top" skus="C220"]

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Target
sCD22
Product Type
Polyclonal Antibody
Alternate Names
BL-CAM, MGC130020, SIGLEC2
Applications
ELISA Cap
,
ELISA Indirect
,
N
,
WB

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Product Size
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
Purified Recombinant Human sCD22 (>98%)
Formulation
This antigen affinity purified polyclonal antibody is aseptically filtered and lyophilized from PBS with no carrier proteins or preservatives added.
Storage and Handling
The lyophilized antibody should be stored desiccated at -20°C. The reconstituted antibody can be stored for at least six weeks at 4°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human Soluble CD22 (sCD22) recognizes Human sCD22. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
Antigen Distribution
Human CD22 is present in the cytoplasm of nearly all B-lineage cells and is also expressed on the surface of B-cells during advance stages of differentiation.
Background
Cluster of differentiation 22 also known as CD22 is a B-cell-restricted transmembrane protein, which acts as a negative regulator of B-cell signalling. CD22 also has lectin-like adhesive properties.1 CD22 is a good target to shorten the time required for Ab production, thereby augmenting host defense against acute infectious diseases as "universal vaccination."2

Antigen Details

PubMed

References & Citations

1. Crocker PR et al. (2000) Immunol. 101: 342 2. Tsubata T et al. (2008) J Immunol. 180: 907
Elisa Sandwich Protocol
Indirect Elisa Protocol
N
General Western Blot Protocol
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.