Rabbit Anti-Human CD82
Data
- -
- -
Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Immunogen This CD82 polyclonal antibody used a peptide immunogen located within the last 50 amino acids of CD82 also known as KAI1. Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2828672 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Anti-Human CD82 recognizes Human CD82. This polyclonal antibody was purified using peptide affinity chromatography. Antigen Distribution Monocytes, granulocytes,lymphocytes, epithelial cells, endothelial cells, fibroblasts Background CD82, also known as KAI1, C33 and TSPAN27 is a metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. It is believed that this protein plays a role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. It associates with IGSF8, DARC, the ganglioside GM2, and the HTLV-1 Gag protein. Antigen DetailsFunction Signal transduction, adhesion, tumor metastasis suppressor NCBI Gene Bank ID Research Area Immunology Technical Protocols |
Related Products
Products are for research use only. Not for use in diagnostic or therapeutic procedures.