Anti-Human CD51 (Clone 13C2) – PE
Anti-Human CD51 (Clone 13C2) – PE
Product No.: C639
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Clone 13C2 Target CD51 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Integrin alphaV Isotype IgG1 Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Human Osteoclastoma Tissue Formulation This conjugate is formulated in phosphate buffered saline (PBS), 1 mg/ml BSA and 10 mM sodium azide as a preservative. Storage and Handling Store at 2-8°C protected from light. DO NOT FREEZE. For long term storage aliquot conjugate into working volumes and store at 2-8°C for up to a year. Country of Origin USA Shipping Next Day 2-8°C Excitation Laser Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm) RRIDAB_2829794 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Anti-Human CD51 (Clone 13C2) recognizes Human CD51. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-Human CD51 recognizes the (Mr 110/90 kDa) antigen known as the alpha-chain of the vitronectin receptor (VNR). This forms a complex with the CD61 antigen and mediates cell adhesion to RGD (arg-gly-asp) containing sequences in vitronectin, von Willebrand factor, fibrinogen and thrombospondin. This antibody reacts with osteoclasts, placenta and melanoma cell lines, some endothelial cells, smooth muscle cells and fibroblasts, and weakly with platelets. Antigen DetailsLigand/Receptor Vitronectin, von Willebrand factor, fibrinogen, thrombospondin, osteopontin, denatured collagen, fibronectin, laminin. PubMed NCBI Gene Bank ID UniProt.org References & Citations1. Strobel, I. et al. (2000) Gene Therapy 7:2028
2. Leukocyte Typing IV (1989) Oxford University Press
3. Davies, J. et al. (1989) J. Cell Biol. 109:1817
4. Horton, M. A. et al. (1985) Cancer Research 45: 5663 Technical Protocols |
Formats Available
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Prod No. | Description |
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C637 | |
C639 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.