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Anti-Human CDw60 (CDw60)
Allophycocyanin (APC)
(9-0-acetyl GD3)
Monoclonal Antibody
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Prod. No.:C326
Clone:Jones
Isotype:Mouse IgM
Conc.:0.1 mg/ml
Pkg. Size:50 µg, 100 µg, 200 µg
Description
Specificity:
Mouse Anti-Human CDw60 (Clone Jones) recognizes Human CDw60. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-Human CDw60 recognizes a (Mr 120 kD) carbohydrate (9-0-acetyl GD3) antigen.

Antigen Distribution:
The CDw60 antigen is present on gangliosides, platelets and a subset of CD4+, CD8+ peripheral T-cells, but not on B-cells, monocytes or granulocytes. CDw60 is involved in the co-stimulation of T-cells. The antigen is also detectable in some previously undescribed benign and malignant tumors. CDw60 shows different subcellular distribution patterns.

Reporter Molecule:
Allophycocyanin (APC) has a molecular weight of 104 kDa and is purified from green algae. APC is an intensely bright phycobiliprotein with a broad absorption profile that peaks at ~650 nm, and a fluorescence emission maximum of ~660 nm.

Known Species Cross Reactivity: Ms+, Hu+, Rt+
Host Species
Mouse
Formulation
This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This APC conjugate is stable when stored at 2-8°C. Do not freeze.
Reported Applications
FC
Each investigator should determine their own optimal working dilution for specific applications.


Country of Origin
USA
References
1. Leukocyte Typing V (1995) Oxford University Press
2. Blum, A. S. and Barnstable, C. J. et al. (1987) Proc. Natl. Acad. Sci. 84:8716
3. Constantine-Paton, M. et al. (1986) Nature 324:659
Related Products
Anti-Human CDw60 (9-0-acetyl GD3) Purified (Leinco Prod. No.: C291)
Anti-Human CDw60 (9-0-acetyl GD3)-R-phycoerythrin (R-PE) (Leinco Prod. No.: C294)
Anti-Human CDw60 (9-0-acetyl GD3)-Fluorescein (FITC) (Leinco Prod. No.: C293)
Anti-Human CDw60 (9-0-acetyl GD3)-Biotin (Leinco Prod. No.: C292)
PN:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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