Anti-Human Dtk (Clone 96201)
Anti-Human Dtk (Clone 96201)
Product No.: D354
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Clone 96201 Target Dtk Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Developmental Receptor Tyrosine Kinase Isotype IgG1 Applications ELISA Cap , FC , IHC FFPE |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified Recombinant Human Dtk (Accession # Q06418) Endotoxin Level <0.1 EU/µg as determined by the LAL method Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. Storage and Handling The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2829934 Applications and Recommended Usage? Quality Tested by Leinco ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. The suggested coating concentration is 2-8 µg/ml. A suitable detection antibody is PN:D366 at a concentration of approximately 300 µg/ml. A suggested standard for this assay is PN:D338. Flow Cytometry: Suitable for use at concentration of 0.25 µg/106 cells. Additional Applications Reported In Literature ? IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 8 µg/ml. The recommended secondary antibody for IHC is PN:M114. For chromogenic detection with high signal and low background use PN:D100 or PN:K107. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Anti-Human Developmental Receptor Tyrosine Kinase (Dtk) (Clone 96201) recognizes an epitope on Human Dtk. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Dtk belongs to a recently recognized subfamily of receptor tyrosine kinases that also includes Ufo (Axl/Ark) and Mer (Eyk). Ligands for Dtk and Ufo have been identified as protein S and the related molecule Gas6, respectively. Dtk is likely to be involved in the regulation of hematopoiesis, particularly during the embryonic stages of blood cell development. 1 DTK is also abundantly expressed in adult kidney, testis, and ovary. 2 Antigen DetailsPubMed NCBI Gene Bank ID UniProt.org References & Citations1. Crosier, KE.et al.(1996)Exp Hematol24:318 2. Crosier, PS.et al.(1994)Growth Factors11:137 Technical Protocols  IHC FFPE |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
