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Rabbit Anti-Human Neurturin (NRTN)
Purified No Carrier Protein
(NTN)
Polyclonal Antibody
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Prod. No.:N132
Host:Rabbit
Conc.:0.5 mg/ml
Pkg. Size:0.1 mg, 0.5 mg, 1 mg
Storage:2-8°C Detailed storage instructions below.
Description
Specificity:
Rabbit Anti-Human Neurturin (NTN) recognizes Human NTN. This polyclonal antibody was purified using affinity chromatography.

Background:
Neurturin (NRTN) is a potent neurotrophic factor.1 NRTN supports the survival of cultured sympathetic neurons and sensory neurons of the nodose and dorsal root ganglia. Neurturin is structurally related to GDNF (Glial cell line-derived neurotrophic factor).2 NRTN has been demonstrated to act specifically on mesencephalic dopaminergic neurons, suggesting its therapeutic potential for Parkinson's disease (PD).3

Known Species Cross Reactivity: Hu+
Immunogen
Neurturin Blocking Peptide (Leinco Prod. No.: N162)
Blocking Peptide
Neurturin Blocking Peptide (Leinco Prod. No.: N162)
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Stability
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), WB
Each investigator should determine their own optimal working dilution for specific applications.


Country of Origin
USA
References
1. Jeffrey Milbrandt et al. (1997) Genomics 44: 137
2. Kotzbauer et al. (1996) Nature 384: 467
3. Sheng-Di Chen et al. (2007) Molec. Neurodegeneration 2: 19
Related Products
Neurturin Blocking Peptide (Leinco Prod. No.: N162)
Anti-Human Neurturin (Leinco Prod. No.: N202)
Anti-Human Neurturin (Antigen Aff. Pur.) (Leinco Prod. No.: M186)
Anti-Human Neurturin-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: N181)
Anti-Human Neurturin (Leinco Prod. No.: N203)
Recombinant Human Neurturin (Leinco Prod. No.: N120)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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