Anti-Human Neurturin
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Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Immunogen PN:N162 Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2831400 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Anti-Human Neurturin (NTN) recognizes Human NTN. This polyclonal antibody was purified using affinity chromatography. Background Neurturin (NRTN) is a potent neurotrophic factor.1 NRTN supports the survival of cultured sympathetic neurons and sensory neurons of the nodose and dorsal root ganglia. Neurturin is structurally related to GDNF (Glial cell line-derived neurotrophic factor).2 NRTN has been demonstrated to act specifically on mesencephalic dopaminergic neurons, suggesting its therapeutic potential for Parkinson's disease (PD).3 Antigen DetailsPubMed NCBI Gene Bank ID UniProt.org References & Citations1. Jeffrey Milbrandt et al. (1997) Genomics 44: 137
2. Kotzbauer et al. (1996) Nature 384: 467
3. Sheng-Di Chen et al. (2007) Molec. Neurodegeneration 2: 19
Technical ProtocolsIHC FFPE  |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
