Recombinant Human Neurturin

Home/Recombinant Proteins/Recombinant Human Neurturin

Pricing & Details

Product. No.N120
Alternate Names
NTN
Expression Host
E. coli
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
N120-20 µg
20 µg
$315.00
In stock
Max:
Min: 1
Step: 1

Background

Neurturin (NRTN) is a potent neurotrophic factor.1 NRTN supports the survival of cultured sympathetic neurons and sensory neurons of the nodose and dorsal root ganglia. Neurturin is structurally related to GDNF (Glial cell line-derived neurotrophic factor).2 NRTN has been demonstrated to act specifically on mesencephalic dopaminergic neurons, suggesting its therapeutic potential for Parkinson's disease (PD).3

Protein Details

Purity
>95% by SDS Page and analyzed by silver stain.
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human NRTN was determined by its ability to support survival of a majority of newborn Rat Sympathetic neurons at a concentration of 100 ng/ml.
Expression Host
E. coli
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human NRTN, which consists of two disulfide linked homodimers, is Mr 23.6 kDa.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Milbrandt, J. et al. (1997) Genomics 44: 137
2. Kotzbauer et al. (1996) Nature 384: 467
3. Chen, SD. et al. (2007) Molec. Neurodegeneration 2: 19
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok