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Anti-Human CD11c
PerCP
(gp 150/95)
Monoclonal Antibody
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Prod. No.:C1691
Clone:3.9
Isotype:Mouse IgG1
Conc.:0.1 mg/ml
Pkg. Size:50 µg, 100 µg, 200 µg
Storage:2-8°C Detailed storage instructions below.
Description
Specificity:
Mouse Anti-Human CD11c (Clone 3.9) recognizes an epitope on Human CD11c. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution:
The CD11c antigen is present on monocytes and in lower density on granulocytes and NK cells. The antigen is strongly expressed in hairy cell leukemia and in some acute myeloid leukemias. Anti-Human CD11c (clone 3.9) stains macrophages in acetone-fixed frozen section of human lung, brain, colon, skin, spleen, thymus and tonsil.

Background:
Anti-Human CD11c may be used to stain monocytes and macrophages or hairy cell leukemia cells. This antibody can be used in studies of complement receptors. In malignant tissue, Anti-CD11c stains true histiocytic lymphomas and does not stain carcinomas or T- or B-lymphomas.

Reporter Molecule:
PerCp is a component of the photosynthetic apparatus found in the dinoflagellate Glenodinium. PerCP is a protein complex with a molecular weight of ~35 kDa. Due to its photobleaching characteristics do not use on flow cytometers with high-power lasers.

Known Species Cross Reactivity: Hu+
Host Species
Mouse
Immunogen
Purified Recombinant Human CD11c (>98%)
Formulation
This PerCP conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This PerCP conjugate is stable when stored at 2-8°C. Do not freeze.
Reported Applications
FC
Each investigator should determine their own optimal working dilution for specific applications.


Country of Origin
USA
References
1. Leukocyte Typing V (1995) Oxford University Press
2. Leukocyte Typing IV (1989) Oxford University Press
3. Leukocyte Typing III (1987) Oxford University Press
4. Hogg, N. et al. (1986) Eur. J. Immunol. 16:240
5. Malhotra, V. et al. (1986) Eur. J. Immunol. 16:1117
Related Products
Anti-Human CD11c (gp 150/95)-Fluorescein (FITC) (Leinco Prod. No.: C147)
Anti-Human CD11c (gp 150/95) Purified (Leinco Prod. No.: C145)
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Anti-Human CD11c (gp 150/95)-Biotin (Leinco Prod. No.: C146)
Anti-Human CD11c (gp 150/95) Purified Low Endotoxin Functional Formulation (Leinco Prod. No.: C369)
Anti-Human CD11c (gp 150/95)-R-phycoerythrin (R-PE) (Leinco Prod. No.: C148)
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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