Anti-Gαo Protein – Purified

Anti-Gαo Protein – Purified

Product No.: G105

[product_table name="All Top" skus="G105"]

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Clone
2A
Target
Gαo Protein
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
IgG1
Applications
IHC FFPE
,
IP
,
WB

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Select Product Size
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Antibody Details

Product Details

Reactive Species
Bovine
Host Species
Mouse
Immunogen
Purified Recombinant Bovine Gαo Protein (>98%)
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
The anti Gαo protein antibody 2A recognizes Gαo protein from bovine, human, rat and mouse.
Antigen Distribution
Antibody 2A reacts with bovine Gαo protein. Antibody showed 70% reactivity in human, 61% in rat and 54% in mouse of the bovine reactivity.
Background
Heterotrimeric G proteins, composed of Gα and Gβγ subunits, transmit signals from cell surface receptors to cellular effector enzymes and ion channels. The Gαo protein is the most abundant Gα subtype in the nervous system, but it is also found in the heart. Its function is not completely known, although it is required for regulation of N-type Ca2+ channels in GH3 cells and also interacts with GAP43, a major protein in growth cones, suggesting a role in neuronal pathfinding.

Antigen Details

Research Area
Apoptosis
.
Cell Biology
.
Immunology

References & Citations

1. Li, X. et al. (1995) J. Neurochemistry 64:1107
IHC FFPE
Immunoprecipitation Protocol
General Western Blot Protocol

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.