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Anti-Human HLA-DR Monomorphic
R-phycoerythrin (R-PE)
Monoclonal Antibody
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Prod. No.:H134
Clone:L243
Pkg. Size:50 µg, 100 µg, 200 µg
Description
Specificity:
Anti-Human HLA-DR recognizes the HLA-DR class II major histocompatibility antigen. HLA-DR is a transmembrane glycoprotein composed of alpha and beta subunits with molecular weights of 36 kDa and 27 kDa, respectively.1 Anti HLA-DR (Clone L243) reacts with a monomorphic determinant and does not cross react with HLA-DQ or HLA-DP.2

Antigen Distribution:
The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.

Reporter Molecule:
R-phycoerythrin (R-PE) has a molecular weight of 240 kDa and is purified from red algae. R-PE is an intensely bright phycobiliprotein with an absorption maxima at approximately 496, 546 and 565 nm, and a fluorescence emission maximum of ~578 nm.

Host Species
Mouse
Formulation
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.


Country of Origin
USA
References
1. Lampson, L. A. et al. (1980) J. Immunol. 125:393
2. Yu, D. T. Y. et al. (1980) J. Exp. Med. 151:91
3. Warnke, R. et al. (1980) N. Eng. J. Med. 303:293
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Anti-Human HLA-DR Monomorphic Purified (Leinco Prod. No.: H131)
Anti-Human HLA-DR Monomorphic Purified - No Carrier Protein (Leinco Prod. No.: H261)
PN:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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