Anti-Human HLA-DR Monomorphic – Purified (PhenoCyler-Fusion (CODEX)® Ready)
Anti-Human HLA-DR Monomorphic – Purified (PhenoCyler-Fusion (CODEX)® Ready)
Product No.: H500
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Clone L243 Target HLA-DR Monomorphic Formats AvailableView All Product Type Monoclonal Antibody Isotype IgG2a Applications IHC FF , PhenoCycler® |
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CODEX® DetailsValidation Notes Clone L243 has been validated for use on CODEX® using human tonsil Fresh Frozen (FF) tissue. Tissue Screened Tonsil Tissue Preparation FF (Fresh Frozen) Antibody and Reporter DetailsReactivity Species Baboon ⋅ Chimpanzee ⋅ Cynomolgus Monkey ⋅ Marmoset ⋅ Rhesus Monkey ⋅ Squirrel Monkey ⋅ Canine ⋅ Human Host Species Mouse Concentration 0.5 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4. Storage and Handling This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Applications and Recommended Usage? Quality Tested by Leinco CODEX® This HLA-DR (Clone L243) antibody is formulated to simplify the antibody preparation needed when performing a CODEX® barcode conjugate. The suggested concentration is 0.5 mg/ml. RRID AB_2893765 Country of Origin USA Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Human HLA-DR recognizes the HLA-DR class II major histocompatibility antigen. HLA-DR is a transmembrane glycoprotein composed of alpha and beta subunits with molecular weights of 36 kDa and 27 kDa, respectively.1 Anti HLA-DR (Clone L243) reacts with a monomorphic determinant and does not cross react with HLA-DQ or HLA-DP.2 Antigen Distribution The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas. Antigen DetailsProtein Ligand/Receptor CD3/TCR, CD4 PubMed References & Citations1. Wright, TM. et al. (2001) Arthritis Rheum. 44(7):1654-9. Article Link 2. Lampson, LA. et al. (1980) J. Immunol. 125:393 3. Yu, D. et al. (1980) J. Exp. Med. 151:91 4. Warnke, R. et al. (1980) N. Eng. J. Med. 303:293 5. Wilkinson, KA. et al. (2005) Infect Immun. 74(5):2991-8 Technical Protocols PhenoCycler® |
Formats Available
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Prod No. | Description |
|---|---|
H131 | |
H132 | |
H133 | |
H1636 | |
H1637 | |
H1638 | |
H1640 | |
H500 | |
H134 | |
H261 | |
H241 | |
H461 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
