Product Datasheet
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Recombinant Human Vaspin
Purified No Carrier Protein
(Serpin A12, OL-64, Visceral Adipose Tissue-Derived Serpin)
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Size


Prod. No.:V112
SourceE. coli
Pkg. Size:20 µg
Storage:-20°C Detailed storage instructions below.
Description
Background:
Visceral adipose tissue-derived serpin (vaspin) is a novel adipokine related to obesity and its metabolic consequences.1 Vaspin is a member of serine protease inhibitor family.2 Its levels increase with hyperinsulinemia and obesity.3 vaspin exerts an insulin-sensitizing effect targeted toward white adipose tissues (WAT) in states of obesity.2

Source
E. coli
State of Matter
Purity
>98% by SDS-PAGE and HPLC
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
MLKPSFSPRN YKALSEVQGW KQRMAAKELA RQNMDLGFKL LKKLAFYNPG RNIFLSPLSI STAFSMLCLG AQDSTLDEIK QGFNFRKMPE KDLHEGFHYI IHELTQKTQD LKLSIGNTLF IDQRLQPQRK FLEDAKNFYS AETILTNFQN LEMAQKQIND FISQKTHGKI NNLIENIDPG TVMLLANYIF FRARWKHEFD PNVTKEEDFF LEKNSSVKVP MMFRSGIYQV GYDDKLSCTI LEIPYQKNIT AIFILPDEGK LKHLEKGLQV DTFSRWKTLL SRRVVDVSVP RLHMTGTFDL KKTLSYIGVS KIFEEHGDLT KIAPHRSLKV GEAVHKAELK MDERGTEGAA GTGAQTLPME TPLVVKIDKP YLLLIYSEKI PSVLFLGKIV NPIGK


Country of Origin
USA
References
1. Blüher M.et al. (2008) Atherosclerosis
2. Kanwar YS. et al. (2005) Proc Natl Acad Sci USA 102: 10610
3. Randeva HS et al. (2008) Diabetes 57: 1501
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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