Bim (Intermediate Domain-2) Blocking Peptide [B491] : Leinco Technologies, excellence in early discovery research

0 $0.00

Product Datasheet

www.leinco.com

excellence in early discovery research

Bim (Intermediate Domain-2) Blocking Peptide

(BOD)

Blocking Peptide

Share |

Size

50 µg ( $115.00 )

Add to Cart:

Prod. No.:	B491
Conc.:	0.2 mg/ml
Pkg. Size:	50 µg
Storage:	-20°C Detailed storage instructions below.

Description

Background:

Bim peptide is applicable as a control peptide for blocking antibody binding in Western blotting.

Amino Acid Location

16 amino acids near the middle of human Bim.

Formulation

This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.

Storage and Stability

Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Reported Applications

FC, N

Neutralization: The peptide may be used to neutralize the binding activity of Anti-Human Bim (Intermediate Domain-2) (Leinco Prod. No.: B460) by incubation of an equal volume of the peptide and antibody for 30 minutes at 37°C for Western blotting experiments.

Each investigator should determine their own optimal working dilution for specific applications.

Country of Origin

USA

References

1. Cory S, Huang DCS, and Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22:8590-607.

2. Heiser D, Labi V, Erlacher M, et al. The Bcl-2 protein family and its role in the development of neoplastic disease. Exp. Geron. 2004; 39:1125-35.

3. Ottilie S, Diaz JL, Horne W, et al. Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins. J. Biol. Chem. 1997; 272:30866-72.

4. Zhou XM, Liu Y, Payne G, et al. Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155. J. Biol. Chem. 2000; 275:25046-51.