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Recombinant Mouse VCAM-1
Purified No Carrier Protein
(Vascular Cell Adhesion Molecule 1, CD106, INCAM-100, VLA4)
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Prod. No.:V125
SourceNSO Cells
Pkg. Size:50 µg, 200 µg, 1 mg
Storage:-20°C to -70°C Detailed storage instructions below.
Description
Background:
Vascular cell adhesion molecule 1, also known as VCAM1 is an immunoglobulin-like adhesion molecule expressed on activated endothelial cells.1 This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. VCAM-1 promotes the adhesion of lymphocytes, monocytes, eosinophils, and basophils.

Source
NSO Cells
Molecular Weight
The predicted molecular weight of Recombinant Mouse VCAM-1 is Mr 101.9 kDa (monomer). However, the actual molecular weight as observed by migration on SDS Page is Mr 120 kDa.
State of Matter
Lyophilized
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Purity
>90% by SDS-PAGE and analyzed by silver stain.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Endotoxin
<1.0 EU/µg as determined by the LAL method
Amino Acid Sequence
mfkieis peyktiaqig dsmaltcstt gcesplfswr tqidsplnak vrtegsksvl tmepvsfene hsylctatcg sgklersihv diysfpkdpe iqfsgplevg kpvtvkclap diypvyrlei dlfkgdqlmn rqefsseemt ksletkslev tftpviedig kalvcraklh idqidstlke retvkelqvy isprnttisv hpstrlqegg avtmtcsseg lpapeifwgr kldnevlqll sgnatltlia mrmedsgvyv cegvnligrd kaevelvvqe kpfivdispg sqvaaqvgds vvltcaaigc dspsfswrtq tdsplngvvr negakstlvl ssvgfedehs ylcavtclqr tlekrtqvev ysfpedpvik msgplvhgrp vtvnctvpnv ypfdhleiel lkgettlmkk yfleemgiks letkilettf iptiedtgks lvclarlhsg emesepkqrq svqplyvnva pkettiwvsp spileegspv nltcssdgip apkilwsrql nngelqplse nttltfmstk rddsgiyvce gineagisrk sveliiqvsp kdiqltvfps ksvkegdtvi isctcgnvpe twiilkkkak tgdmvlksvd gsytirqaql qdagiyeces ktevgsqlrs ltldvkgkeh nkdyfspeie grmdpkscdk thtcppcpap ellggpsvfl fppkpkdtlm isrtpevtcv vvdvshedpe vkfnwyvdgv evhnaktkpr eeqynstyrv vsvltvlhqd wlngkeykck vsnkalpapi ektiskakgq prepqvytlp psrdeltknq vsltclvkgf ypsdiavewe sngqpennyk ttppvldsdg sfflyskltv dksrwqqgnv fscsvmheal hnhytqksls lspgkhhhhh h



Country of Origin
USA
References
1. Yuqing Huo et al. (2001) J Clin Invest 107: 1209
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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