Recombinant Mouse VCAM-1

Recombinant Mouse VCAM-1

Product No.: V125

[product_table name="All Top" skus="V125"]

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Prod. No.V125
Expression Host
NS0 Cells

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Select Product Size
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Background

Vascular cell adhesion molecule 1, also known as VCAM1 is an immunoglobulin-like adhesion molecule expressed on activated endothelial cells.2 This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. VCAM-1 promotes the adhesion of lymphocytes, monocytes, eosinophils, and basophils.

Protein Details

Purity
>90% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Fusion Protein Tag
Fc Fusion Protein
Protein Accession No.
Amino Acid Sequence
mfkieis peyktiaqig dsmaltcstt gcesplfswr tqidsplnak vrtegsksvl tmepvsfene hsylctatcg sgklersihv diysfpkdpe iqfsgplevg kpvtvkclap diypvyrlei dlfkgdqlmn rqefsseemt ksletkslev tftpviedig kalvcraklh idqidstlke retvkelqvy isprnttisv hpstrlqegg avtmtcsseg lpapeifwgr kldnevlqll sgnatltlia mrmedsgvyv cegvnligrd kaevelvvqe kpfivdispg sqvaaqvgds vvltcaaigc dspsfswrtq tdsplngvvr negakstlvl ssvgfedehs ylcavtclqr tlekrtqvev ysfpedpvik msgplvhgrp vtvnctvpnv ypfdhleiel lkgettlmkk yfleemgiks letkilettf iptiedtgks lvclarlhsg emesepkqrq svqplyvnva pkettiwvsp spileegspv nltcssdgip apkilwsrql nngelqplse nttltfmstk rddsgiyvce gineagisrk sveliiqvsp kdiqltvfps ksvkegdtvi isctcgnvpe twiilkkkak tgdmvlksvd gsytirqaql qdagiyeces ktevgsqlrs ltldvkgkeh nkdyfspeie grmdpkscdk thtcppcpap ellggpsvfl fppkpkdtlm isrtpevtcv vvdvshedpe vkfnwyvdgv evhnaktkpr eeqynstyrv vsvltvlhqd wlngkeykck vsnkalpapi ektiskakgq prepqvytlp psrdeltknq vsltclvkgf ypsdiavewe sngqpennyk ttppvldsdg sfflyskltv dksrwqqgnv fscsvmheal hnhytqksls lspgkhhhhh h
N-terminal Sequence Analysis
Met
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse VCAM-1 is Mr 101.9 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 120 kDa.
Predicted Molecular Mass
101.9
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Sriramarao, P. et al. (2018) Am J Physiol Lung Cell Mol Physiol. 315(2):L227-L240. PubMed
2. Huo, Y. and Ley, K. (2001) J Clin Invest 107: 1209
Elisa Sandwich Protocol
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.