Recombinant Mouse VCAM-1

Vascular cell adhesion molecule 1, also known as VCAM1 is an immunoglobulin-like adhesion molecule expressed on activated endothelial cells.² This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. VCAM-1 promotes the adhesion of lymphocytes, monocytes, eosinophils, and basophils.

Fc Fusion Protein

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Met

Lyophilized

The predicted molecular weight of Recombinant Mouse VCAM-1 is Mr 101.9 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 120 kDa.

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Sriramarao, P. et al. (2018) Am J Physiol Lung Cell Mol Physiol. 315(2):L227-L240. PubMed
2. Huo, Y. and Ley, K. (2001) J Clin Invest 107: 1209