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Recombinant Rat RANTES (RANTES)
(CCL5, D17S136E, MGC17164, SCYA5, SIS-Delta, TCP228)
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Prod. No.:R134
SourceE. Coli
Pkg. Size:5 µg, 25 µg, 100 µg, 1 mg
Description
Background:
RANTES also known as Chemokine (C-C motif) ligand 5 (CCL5), a CC-chemokine1 is an important mediators of the immune and inflammatory response.2 It is also a potent chemoattractant for T cells 3 and eosinophils.4 RANTES is involved in many inflammatory diseases, for example, bronchial asthma, delayed-type hypersensitivity reactions, viral infections, arthritis, chronic eosinophilic pneumonia, and idiopathic interstitial pneumonia.5

Source
E. Coli
State of Matter
Purity
>98% by SDS Page
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Endotoxin
<1.0 EU/µg
Biological Activity
The biological activity of Rat Regulation Upon Activation Normal T Cell Express Sequence is determined by its ability to chemoattract rat peritoneal macrophages using a concentration range of 50.0-100.0 ng/ml.
Each investigator should determine their own optimal working dilution for specific applications.
Amino Acid Sequence
SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS


Country of Origin
USA
References
1. Lee SC et al. (2004) J Neurochem. 90: 297
2. Borkowski J et al. (2004) Arch Immunol Ther Exp (Warsz) 52: 201
3. Geiger H et al. (2005) Kidney Blood Press Res 28: 48
4. Hirata I. et al. (2008) Dig Dis Sci.
5. Emilie D et al. (1994) J Exp Med. 179: 1689
Related Products
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Human RANTES ELISA Development Kit (Leinco Prod. No.: R1270)
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Anti-Mouse RANTES-Biotin (Antigen Aff. Pur.) (Leinco Prod. No.: R141)
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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