Recombinant Human Ephrin-B3

Ephrin-B3, also known as EFNB3, is a member of the ephrin gene family. Ephrin-B3 is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression are particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system.

Fc Fusion Protein

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Leu28

Lyophilized

The predicted molecular weight of Recombinant Human Ephrin-B3 is Mr 48.3 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 57-61 kDa.

48.3

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Holen, HL. et al. (2011) Scand. J. Immunol. 74:144.
2. Xu, NJ. et al. (2011) Nat. Neurosci. 14:1421.