Anti-Clostridium difficile, GDH (CDIF-0294)
Anti-Clostridium difficile, GDH (CDIF-0294)
Product No.: C010
- -
- -
Clone CDIF-0294 Target GDH Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Alternate Names GDH, glutamate dehydrogenase, C. diff, C. difficile Isotype Mouse IgG1 Applications ELISA |
- -
- -
Antibody DetailsProduct DetailsReactivity Species Clostridium difficile Host Species Mouse Product Concentration ≥1.0 mg/ml Purity ≥90% Formulation Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1:20-1:200 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Matched Pair Best ELISA pair (capture/detection), CDIF-0294/CDIF-6581 Background Clostridium difficile, often referred to as C. diff, is an anaerobic, Gram-positive bacterium that can cause a range of gastrointestinal issues in humans. Infections with C. difficile are primarily associated with healthcare settings such as hospitals and long-term care facilities where patients come into contact with infected individuals or contaminated surfaces1. C. diff infections (CDIs) typically occur following the disruption of the normal gut microbiota, often due to antibiotics, which allow the bacteria to proliferate and produce toxins2.
Glutamate dehydrogenase (GDH) is an enzyme produced by C. difficile which is responsible for conversion of glutamate to alpha-ketoglutarate. GDH detection in the stool is often used as a rapid screening tool to suggest possible presence of C. diff. Further testing for the bacterial toxins is typically performed upon a positive GDH test. Antigen DetailsResearch Area Bacteria . Infectious Disease . Matched Pair . Nosocomial References & Citations1. Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Healthcare Quality Promotion (DHQP), Link
2. Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Healthcare Quality Promotion (DHQP), Link Technical Protocols |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
