Anti-Listeria monocytogenes, p60 (LMON-3236)
Anti-Listeria monocytogenes, p60 (LMON-3236)
Product No.: L323
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Clone LMON-3236 Target p60 Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Isotype Mouse IgG2b Applications ELISA |
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Antibody DetailsProduct DetailsReactivity Species Listeria monocytogenes Host Species Mouse Product Concentration ≥1.0 mg/ml Purity ≥90% Formulation Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1:20-1:200 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Listeria monocytogenes (Clone LMON-3471) is specific for the secreted p60 protein of L. monocytogenes. Matched Pair Best ELISA pair (capture/detection), LMON-3236/LMON-3471 Background Listeria is a genus of Gram-positive, rod-shaped bacteria that includes the species Listeria monocytogenes, the primary pathogenic member responsible for causing listeriosis in humans. Unlike many other bacteria, Listeria is capable of growing and reproducing in a wide range of environments, including both refrigerated and room temperatures. This adaptability contributes to its potential for contaminating various foods, leading to foodborne outbreaks. Listeria monocytogenes is known for its ability to survive and replicate within host cells, enabling it to cross intestinal and placental barriers, resulting in diverse clinical manifestations. While healthy individuals might experience mild or no symptoms, listeriosis can lead to severe illness in vulnerable populations, such as pregnant women, newborns, the elderly, and immunocompromised individuals1. p60, is a murein hydrolase that is an essential virulence factor for Listeria. It is secreted in large quantities and is involved in the invasion of host cells2. Antigen DetailsResearch Area Bacteria . Category B Pathogens . Infectious Disease . Matched Pair References & Citations1. Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Foodborne, Waterborne, and Environmental Diseases. Link
2. Carvalho, F., Sousa, S., & Cabanes, D. (2014). How listeria monocytogenes organizes its surface for virulence. Frontiers in Cellular and Infection Microbiology, 4. https://doi.org/10.3389/fcimb.2014.00048 Technical Protocols |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
