Anti-Thyroglobulin Mouse Monoclonal Antibody – Library Pack (121101)

Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid. Thyroglobulin accounts for approximately half of the protein content of the thyroid gland. Human TG is a homodimer of subunits each containing 2768 amino acids as synthesized (a short signal peptide may be removed from the N-terminus in the mature protein). Tg is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3).

Purified human thyroglobulin.

12102 is T4-specific and 12104 is T3-specific. 12101 and 12103 recognize both T3 and T4.

Anti-Thyroglobulin Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies:

12101 - Anti-Thyroglobulin Mouse Monoclonal Antibody - Clone TG60 - Isotype IgG1

12102 - Anti-Thyroglobulin Mouse Monoclonal Antibody - Clone TG62 - Isotype IgG1

12103 - Anti-Thyroglobulin Mouse Monoclonal Antibody - Clone TG8.1 - Isotype IgM

12104 - Anti-Thyroglobulin Mouse Monoclonal Antibody - Clone TG9.1 - Isotype IgG1

Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles.

Takeyama M et al. (2012) Biochemistry 51: 820-828.Nogami K et al. (2005) Blood 105: 4362-4368.Fay PJ et al. (2001) J Biol Chem 276: 12434-12439.Fay PJ (1988) Arch Biochem Biophys 262: 525-531. Fay PJ et al. (1986) Biochim Biophys Acta 87: 268-278.