Mikrogen Diagnostik recomLine HEV IgG/IgM Lateral Strip Test Kit (5072)

Hepatitis E virus (HEV) is one of the leading causes of faecal-orally acquired hepatitis worldwide, usually resulting from contaminated drinking water. In developed countries, hepatitis E is usually transmitted through infected pork, which was not sufficiently cooked. HEV can be transmitted through blood products, blood transfusions and organ donation. In Europe most cases of hepatitis E are caused by the HEV genotype 3.

The HEV infection usually remains asymptomatic. Acute hepatitis E is an illness with a clinical presentation comparable to hepatitis A. Typical signs of hepatitis E include flu-like symptoms, vomiting, diarrhoea, fever, arthralgia and headache usually associated with a rise in liver enzyme values. Cholestatic jaundice that develops during the course of disease can persist for several weeks. HEV infection is usually self-limiting. In endemic regions in a high percentage of cases HEV infections during pregnancy follow a fulminant course, accompanied by a high mortality rate of approx. 20%. In males and non-pregnant females the mortality rate is 0.5% - 4.0%.

The recomLine HEV IgG/IgM uses purified recombinant antigens, thus reproducibly ensuring high sensitivity and specificity. The selection of homologous proteins from two different genotypes (genotype 1 and genotype 3) facilitates a high sensitivity also in non-endemic areas with a high percentage of autochthonous cases of hepatitis E.

Research Use Only.

For Sale In the United States Only.

To purchase outside of the US, please contact Mikrogen.