Recombinant Human Ephrin-A3

Ephrin-A3, also known as EFNA3 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin-A3 encodes an EFNA class ephrin.

The biological activity of Human Ephrin-A3 was determined by its ability to compete with biotinylated human Ephrin-A3/Fc (BT359) for binding to immobilized mouse Eph-A6/Fc in a functional ELISA assay.

Fc Fusion Protein

AAA52368

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Asn31

Lyophilized

The predicted molecular weight of Recombinant Human Ephrin-A3 is Mr 47.7 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 60-70 kDa.

47.7

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

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