Recombinant Human Maspin

Maspin is a serine protease inhibitor (serpin) produced by myoepithelial cells that inhibit tumour cell motility, invasion in cell culture, and tumour growth and metastasis.¹ Maspin has been associated with prostate cancer, breast cancer, and tumors of the pancreas.^2,3 It also has prognostic significance for pulmonary adenocarcinoma.⁴

MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP

Lyophilized

The molecular weight of Recombinant Human Maspin is Mr 42.2 kDa.

The protein was 0.2 µm filtered and lyophilized from PBS.

The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Next Day Ambient

1. Craig AD. et al. (2003) J. Pathol. 199: 432 2. Zhang M. et al. (2008) Cancer Res. 68: 5143 3. Morohoshi T. et al. (2008) HBPD Int. 7: 86 4. Toshio et al. (2004) J. of Cancer Res. & Clin Oncol. 130: 475