Anti-BCAS1 / NABC1 Antibody (34017)

Anti-BCAS1 / NABC1 Antibody (34017)

Product No.: 34017

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Target
BCAS1 / NABC1
Product Type
Polyclonal
Alternate Names
Amplified and overexpressed in breast cancer, Novel amplified in breast cancer 1
Applications
IHC
,
WB

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Select Product Size

Data

Immunoblotting : use at 1-5ug/ml. A band of approximately 60 kDa is detectedImmunoblotting : use at 1-5ug/ml. A band of approximately 60 kDa is detected
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
Synthetic peptide corresponding to amino acids 532-550 of human BCAS1/NABC1.
Product Concentration
Lot Specific
Formulation
PBS, pH 7.4.
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
Immunoblotting : use at 1-5ug/mL.A band of approximately 60kDa is detected, however, protein dimerization may occur.

These are recommended concentrations. User should determine optimal concentrations for their applications.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Rabbit Polyclonal Antibody specific to BCAS1/NABC1
Background
Breast Carcinoma Amplified Sequence 1 (BCAS1), also known as Novel Amplified in Breast Cancer 1 (NABC1) was isolated from a region at 20q13 and is amplified in several tumor types. It is associated with more aggressive tumor phenotypes. BCAS1/NABC1 is highly expressed in some, but not all, breast cancer cell lines and in some breast tumors at 20q13.2. The BCAS1/NABC1 gene is predicted to encode a protein of 584 amino acids with no significant homology to other proteins.
Function
Required for myelination. {UniProtKB:Q80YN3}.
NCBI Gene Bank ID
UniProt.org
Research Area
Cancer Research

References & Citations

Chang, N.S et al. Oncogene (2005) 24: 714-723.
Aqeilan, R.I. et al. Cancer Res (2004) 64: 8256-8261.
Sze, C.I. et al. J Biol Chem (2004) 279: 30498-30506.
IHC
General Western Blot Protocol

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.